The first ISCB UK conference will take place in Cambridge, UK, from April 21st to April 22nd 2026. The UK has a large diverse bioinformatics and computational community; this meeting will bring this community together to share cutting-edge science, foster collaborations, and build networks. The programme will feature keynote lectures from internationally recognised leaders, sessions showcasing the latest advances in computational methods and their applications in the life sciences, a vibrant student-led symposium, and plenty of opportunities for networking and community building.