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CMSP News and Views Seminar Series: Modeling of equilibrium and non-equilibrium time-series data: from protein folding to weather forecasting
seminar past active hybrid
Luigi Stasi Seminar Room (Leonardo Building)
More information
Most systems of scientific interest are interacting many-body systems. One typically describes their kinetics in terms of a low-dimensional reaction coordinate, which in general is influenced by the entire system. The dynamics of such a reaction coordinate is governed by the generalized Langevin equation (GLE), an integro-differential stochastic equation, and involves a memory function [1]. I discuss a few examples where the GLE can be used to interpret and model data in different fields of science. Protein-folding kinetics is often described as Markovian (i.e., memoryless) diffusion in a one-dimensional free energy landscape. By analysis of large-scale molecular-dynamics simulation trajectories of fast-folding proteins from the Shaw group using the special-purpose computer ANTON, I demonstrate that the friction characterizing protein folding exhibits significant memory with a decay time that is of the same order as the folding and unfolding times [2]. Memory friction effects lead to anomalous and drastically modified protein kinetics [3]. For the set of proteins for which simulations are available, it is shown that the folding and unfolding times are not dominated by the free-energy barrier but rather by the non-Markovian friction. Memory effects are also present for non-equilibrium systems. Using an appropriate non-equilibrium formulation of the GLE, it is demonstrated that the motion of living organisms is characterized by memory friction, which allows to characterize internal feedback loops of such organisms and to classify and sort individual organisms [3]. The GLE can be even used to predict complex phenomena such as weather data
Thu, Apr 30, 2026
11:00 to Thu, Apr 30, 2026 12:00
Seminar · Hybrid 24
Building networks: engineering in vascular biology
conference past active in_person
EMBL Barcelona · Barcelona, Spain
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This conference will take place at EMBL Barcelona. Vascularisation is a rapidly growing field, with researchers across disciplines recognising its crucial role in organ development, disease progression, and therapeutic delivery. This upcoming edition of the meeting aims to unite researchers working at the intersection of engineering and vascular biology, facilitating discussions on how to apply cutting-edge techniques in spatial omics, advanced imaging, and the use of AI in vascular research.
Wed, May 13, 2026
09:30 to Thu, May 14, 2026 17:35
Conference · In_Person 24
Advanced fluorescence imaging techniques
workshop past active in_person
ISG Hotel · Heidelberg, Germany
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This practical course will cover advanced light microscopy techniques, and participants will learn how to derive qualitative and quantitative insights into molecular mechanisms in cells, tissues and developing organisms. Guest researchers, together with microscopy experts from EMBL, will foster an intensive exchange of information through a balance of lectures and practical workshops. The focus of the course will be on the use of fluorescence microscopy to obtain information about the localisation and functions of proteins and other biomolecules at different spatial scales.
Sun, May 17, 2026
15:30 to Mon, May 18, 2026 16:10
Workshop · In_Person 21
EMBO | EMBL Symposium: Cellular mechanisms driven by phase separation
symposium past active hybrid
EMBL Heidelberg · Heidelberg, Germany
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This interdisciplinary conference brings together scientists from diverse fields to foster new discoveries and discuss emerging principles in condensate biology, ranging from basic biophysical principles of condensate formation to the role intracellular phase transitions play in cellular adaptation and disease.
Tue, May 19, 2026
12:00 to Wed, May 20, 2026 21:00
Symposium · Hybrid 20
ICBP 2026
conference upcoming active in_person
Magazzini del cotone · Genoa, Italy
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12th International Conference on Biological Physics June 28 – July 3 2026 Magazzini del cotone, Genoa, Italy We proudly invite experts in biological physics worldwide to the International Conference on Biological Physics 2026 (ICBP 2026) in the magnificent Italian city of Genoa from June 28 to July 3, 2026. The Italian Society of Pure and Applied Biophysics (SIBPA) is privileged to organise this meaningful conference under the auspices of the International Union of Pure and Applied Physics (IUPAP). Specifically, the Commission on Biological Physics (C6), established by IUPAP in 1990, aims to promote the exchange of information and views among the members of the international scientific community in the general field of Biological Physics.
Audience: researchers
Sun, Jun 28, 2026
09:00 to Fri, Jul 3, 2026 17:00
Conference · In_Person 17
Causality in biomedicine: going beyond associations | EMBL-EBI Training
training upcoming active in_person
Wellcome Genome Campus · Hinxton, United Kingdom
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This course provides an introduction to causal inference and causal representation learning, offering both theoretical foundations and hands-on training. You will learn how to apply these methodologies to various biomedical data types, including clinical, genotype-phenotype, molecular, and multimodal data.
Sun, Oct 4, 2026
09:00 to Thu, Oct 8, 2026 19:00
Training · In_Person 29
Exchange of Experience 2026 | Global BioImaging
conference upcoming active in_person
EMBL · Heidelberg, Germany
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Annual conference for representatives of imaging communities and imaging scientists from around the globe. This event is designed for imaging scientists, core facility managers, technology developers, and industry partners to exchange knowledge, explore emerging trends, and discuss what open access in imaging means globally. Through interactive presentations, hands-on workshops, and regional networking sessions, participants will explore the evolution of open access in imaging worldwide.
Mon, Oct 26, 2026
09:00 to Thu, Oct 29, 2026 17:00
Conference · In_Person 25